IBS (Irritable Bowel Syndrome) affects 10-15% of the population. Ginger addresses three core mechanisms simultaneously — something most IBS medications don't do.
Mechanism 1: Motility Normalization
Ginger is both prokinetic (speeds up slow transit) AND antispasmodic (calms excessive spasms). It modulates 5-HT₃/5-HT₄ receptors — the same targets as alosetron, an IBS drug.
Gastric emptying +25% (Wu 2008) means food moves through at the right pace, reducing both constipation-dominant AND diarrhea-dominant IBS symptoms.
Mechanism 2: Mucosal Anti-Inflammation
NF-κB suppression → reduced mast cell activation → less histamine and serotonin in the gut wall → reduced visceral hypersensitivity (the "amplified pain" of IBS).
Mechanism 3: Microbiome Modulation
Wang 2019: ginger promotes Lactobacillus and Bifidobacterium while reducing gas-producing Clostridium perfringens. A more balanced microbiome = less gas, less bloating.
The Sugar Trap for IBS
Sugar is a known IBS trigger. It ferments in the colon, feeds gas-producing bacteria, and spikes insulin (disrupting motility). A ginger shot with 33g sugar/100ml is essentially a liquid FODMAP.
INTI — 1.1g sugar. Prokinetic + anti-inflammatory + prebiotic. Without the fermentation fuel.
⚠️ IBS requires medical diagnosis (Rome IV criteria). See a gastroenterologist.
Your gut health supplement shouldn't upset your gut.
